By plane
The Felix-Houphouet Boigny International Airport has daily scheduled flights to and from Paris Air France (http://www.airfrance.com/) and Brussels Brussels airlines (http://www.brusselsairlines.com). There are also regular flights to other West-African capitals. The airport is a modern facility and increased security has shaken its old reputation as a place for travelers to be ripped off.
By car
It is ill advised to try to enter Côte d'Ivoire from Guinea, Liberia, Mali, or Burkina Faso. The Ghanaian border is fairly secure. If you enter at Elubo, you can easily catch a shared taxi to Aboisso and then a bus to Abidjan. There are about ten military check-points between the border and Abidjan so have your documents ready. If you do not have proper documentation of your inoculations at the border you will be forced to pay a small fine and they will give you an injection at an on-site clinic.